[Effectiveness of omeprazole therapy in children with gastroesophageal reflux diseases(GERD)].

THE AIM: Of the study was retrospective analysis of omeprazole (Polprazol) therapy efficacy in children with GERD.

MATERIAL AND

METHODS

The analyzed group consisted of 78 children with gastroesophageal reflux disease. GERD was detected on the base of questionnaire, pH-metry and/or endoscopy. The questionnaire was conducted in all patients, 24-hour pH-metric examination in 47% and endoscopy in 53% children. Than omeprazole therapy was introduced (0.5-1.0 mg/kg daily).

RESULTS

Before omeprazole therapy rebounding was observed in 94% children, heartburn in 84%, vomits in 38% and abdominal pain in 90% children. After 8 weeks of therapy analyzed symptoms were significantly reduced--rebounding was observed in 31% children, heartburn in 28% vomits in 5% and abdominal pain in 26% children.

CONCLUSION

Omeprazole therapy is effective in children with gastroesophageal reflux disease.