Raspberry polysaccharide extraction, purification, structural characterization, and biological activity research progress: A review.

Raspberry (Rubus idaeus L.), a plant of significant medicinal and edible value, has garnered considerable attention for its polysaccharides, which exhibit potent biological activities, including anti-inflammatory, antioxidant, antitumor, and immunomodulatory effects. However, the bioefficacy of these polysaccharides is critically dependent on their fine structures, which are, in turn, dictated by the employed extraction and purification methodologies. Consequently, elucidating the intricate process-structure-activity relationship is paramount for their effective utilization. This review provides a comprehensive and systematic synthesis of current research on raspberry polysaccharides, encompassing advanced extraction and purification techniques, methods for structural characterization, underlying mechanisms of biological activity, and potential applications. The objective is to establish a robust scientific framework and practical guidance to facilitate the translation of raspberry polysaccharide research from laboratory-scale investigations to industrial production, thereby providing a foundation for the future development of related functional foods and pharmaceuticals.