Journal of the Medical Association of Thailand = Chotmaihet thangphaet · 2008
Antibiotic prophylaxis for orthognathic surgery: a prospective, comparative, randomized study between amoxicillin-clavulanic acid and penicillin.
Сравнительное исследованиеСтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Jansisyanont Pornchai, Sessirisombat Somchai, Sastravaha Panunn, Bamroong Pimol
Аннотация
OBJECTIVE: The present study was designed to evaluate the prophylactic efficacy after the correction of dentofacial deformities between short- and long-term penicillin and amoxicillin-clavulanic acid.
MATERIAL AND METHOD: The present study was prospective, randomized, and double blinded. Patients were separated into four groups randomly: short-term and long-term (5 days) penicillin and short-term and long-term (5 days) amoxicillin-clavulanic acid.
RESULTS: One hundred twenty two patients were assigned randomly into the four groups. Infection developed in a patient in the short-term amoxicillin-clavulanic acid group and in a patient in the long-term penicillin group.
CONCLUSION: There were no differences in infection between the two groups of antibiotics. Based on the present study, short-term penicillin is still the most appropriate choice for prophylactic antibiotic in orthognathic surgery.
MATERIAL AND METHOD: The present study was prospective, randomized, and double blinded. Patients were separated into four groups randomly: short-term and long-term (5 days) penicillin and short-term and long-term (5 days) amoxicillin-clavulanic acid.
RESULTS: One hundred twenty two patients were assigned randomly into the four groups. Infection developed in a patient in the short-term amoxicillin-clavulanic acid group and in a patient in the long-term penicillin group.
CONCLUSION: There were no differences in infection between the two groups of antibiotics. Based on the present study, short-term penicillin is still the most appropriate choice for prophylactic antibiotic in orthognathic surgery.
Предметные рубрики MeSH
AdolescentAdultAmoxicillin-Potassium Clavulanate CombinationAnti-Bacterial AgentsAntibiotic ProphylaxisBacterial InfectionsDouble-Blind MethodDrug Therapy, CombinationFemaleHumansMaleOsteotomyPenicillinsPostoperative ComplicationsPreoperative CarePrognathismProspective StudiesTemporomandibular JointYoung Adult