Acta psychiatrica Scandinavica · 2009
The relationship between childhood trauma history and the psychotic subtype of major depression.
СтатьяПоддержка NIH: внешняя программаНазвание и аннотация: Перевод в очереди
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Gaudiano B A, Zimmerman M
Аннотация
OBJECTIVE: Increasing evidence exists linking childhood trauma and primary psychotic disorders, but there is little research on patients with primary affective disorders with psychotic features.
METHOD: The sample consisted of adult out-patients diagnosed with major depressive disorder (MDD) at clinic intake using a structured clinical interview. Patients with MDD with (n = 32) vs. without psychotic features (n = 591) were compared as to their rates of different types of childhood trauma.
RESULTS: Psychotic MDD patients were significantly more likely to report histories of physical (OR = 2.81) or sexual abuse (OR = 2.75) compared with non-psychotic MDD patients. These relationships remained after controlling for baseline differences. Within the subsample with comorbid post-traumatic stress disorder, patients with psychotic MDD were significantly more likely to report childhood physical abuse (OR = 3.20).
CONCLUSION: Results support and extend previous research by demonstrating that the relationship between childhood trauma and psychosis is found across diagnostic groups.
METHOD: The sample consisted of adult out-patients diagnosed with major depressive disorder (MDD) at clinic intake using a structured clinical interview. Patients with MDD with (n = 32) vs. without psychotic features (n = 591) were compared as to their rates of different types of childhood trauma.
RESULTS: Psychotic MDD patients were significantly more likely to report histories of physical (OR = 2.81) or sexual abuse (OR = 2.75) compared with non-psychotic MDD patients. These relationships remained after controlling for baseline differences. Within the subsample with comorbid post-traumatic stress disorder, patients with psychotic MDD were significantly more likely to report childhood physical abuse (OR = 3.20).
CONCLUSION: Results support and extend previous research by demonstrating that the relationship between childhood trauma and psychosis is found across diagnostic groups.