Recombinant activated factor VII to control life-threatening haemorrhagic radiation cystitis.

INTRODUCTION

The use of recombinant activated factor VII has been described for many clinical scenarios, but the value of this therapeutic agent for life-threatening haemorrhagic cystitis remains novel.

METHOD: We describe a case of persistent life-threatening haemorrhagic radiation cystitis, and discuss current knowledge of this therapy including potential complications.

RESULT: Control of haemorrhage was successfully achieved only after use of this agent.

CONCLUSION

This therapy deserves mention in any future management algorithm devised for this condition.