Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials · 2005
[Protective effects of the granule of Sambucus chinensis lindl on acute hepatic injury].
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Yang Wei, Wang Xisha, Wang Minwei, Xu Yan, Lu Ding, Liu Changsheng
Аннотация
OBJECTIVE: To investigate the protective effects of the granule of Sambucus chinensis Lindl on acute hepatic injury.
METHODS: The acute liver-injury model induced by CCl4 or D-GalN or ConA was established in mice or rats.
RESULTS: The granule of Sambucus chinensis Lindl showed significantly protective effects on mice acute hepatic injury induced by CCl4 ,and the effects were concern of antagonizing lipoperoxidation and improving energy of Ca2+ -ATPase of theca mitochondria and microsome. It showed significantly protective effects on mice or rats acute hepatic injury induced by D-GalN or Con A, too.
CONCLUSION: The granule of Sambucus chinensis Lindl showed significantly protective effects against many kinds of chemical and immunological liver injuries.
METHODS: The acute liver-injury model induced by CCl4 or D-GalN or ConA was established in mice or rats.
RESULTS: The granule of Sambucus chinensis Lindl showed significantly protective effects on mice acute hepatic injury induced by CCl4 ,and the effects were concern of antagonizing lipoperoxidation and improving energy of Ca2+ -ATPase of theca mitochondria and microsome. It showed significantly protective effects on mice or rats acute hepatic injury induced by D-GalN or Con A, too.
CONCLUSION: The granule of Sambucus chinensis Lindl showed significantly protective effects against many kinds of chemical and immunological liver injuries.