Japanese journal of infectious diseases · 2015
Antibiotic Resistance of Campylobacter jejuni and C. coli Isolated from Children with Diarrhea in Thailand and Japan.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Pham Ngan Thi Kim, Thongprachum Aksara, Tran Dinh Nguyen, Nishimura Shuichi, Shimizu-Onda Yuko, Trinh Quang Duy, Khamrin Pattara, Ukarapol Nuthapong, Kongsricharoern Tipachan, Komine-Aizawa Shihoko, Okitsu Shoko, Maneekarn Niwat, Hayakawa Satoshi, Ushijima Hiroshi
Аннотация
A total of 29 Campylobacter jejuni and C. coli strains were isolated from Thai and Japanese children with diarrhea using the Loop-mediated Isothermal Amplification method. The samples were evaluated for mutations in gyrA and 23S rRNA in order to assess resistance against fluoroquinolones and macrolides, respectively. Among the isolated strains, 9 (8 C. jejuni and 1 C. coli) were from Thai children, and the other 20 (C. jejuni) were isolated from Japanese children. High fluoroquinolone resistance rates were observed in Thai (66.7%) and Japanese (90%) children. Macrolide resistance was not observed in Japanese children but was observed at a considerable rate of 12.5% of C. jejuni isolated in the Thai cohort. The results indicate that continuous monitoring of resistance of Campylobacter strains to fluoroquinolones and macrolides is definitely necessary.