Anais brasileiros de dermatologia · 2017
Stevens-Johnson syndrome and toxic epidermal necrolysis: epidemiological and clinical outcomes analysis in public hospitals.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Arantes Luana Bernardes, Reis Carmélia Santiago, Novaes Alice Garbi, Carvalho Marta Rodrigues de, Göttems Leila Bernarda Donato, Novaes Maria Rita Carvalho Garbi
Аннотация
BACKGROUND: Adverse drug reactions are harmful and involuntary responses to drugs that occur at doses normally used for a given condition. Among them are Stevens-Johnson syndrome and toxic epidermal necrolysis, both rare and potentially fatal conditions.
OBJECTIVES: To analyze the epidemiological and clinical characteristics related to patients diagnosed with Stevens-Johnson syndrome and toxic epidermal necrolysis in public hospitals in the Federal District - Brazil.
METHODS: Retrospective, cross-sectional and descriptive study, in which data were collected referring to patients hospitalized in the public healthcare system of the Federal District from 1999 to 2014. Results: Between 1999 and 2014, 86 cases of hospitalized patients with diagnosis of Stevens-Johnson syndrome and toxic epidermal necrolysis in the Federal District were reported. The majority of patients were women; the most affected age group was 0 to 10 years. Patients older than 60 years (elderly) represent 6.98% of the cases. Most patients admitted to the referral hospital were discharged. However, occurrence of deaths exceeded that of discharge in elderly patients.
LIMITATIONS OF THE STUDY: There is fragility in the registry of hospitalization of patients, both in the hospital information system and in the medical records of the reference hospital.
CONCLUSION: There is a need for greater production and better dissemination of information on the incidence of adverse drug reactions.
OBJECTIVES: To analyze the epidemiological and clinical characteristics related to patients diagnosed with Stevens-Johnson syndrome and toxic epidermal necrolysis in public hospitals in the Federal District - Brazil.
METHODS: Retrospective, cross-sectional and descriptive study, in which data were collected referring to patients hospitalized in the public healthcare system of the Federal District from 1999 to 2014. Results: Between 1999 and 2014, 86 cases of hospitalized patients with diagnosis of Stevens-Johnson syndrome and toxic epidermal necrolysis in the Federal District were reported. The majority of patients were women; the most affected age group was 0 to 10 years. Patients older than 60 years (elderly) represent 6.98% of the cases. Most patients admitted to the referral hospital were discharged. However, occurrence of deaths exceeded that of discharge in elderly patients.
LIMITATIONS OF THE STUDY: There is fragility in the registry of hospitalization of patients, both in the hospital information system and in the medical records of the reference hospital.
CONCLUSION: There is a need for greater production and better dissemination of information on the incidence of adverse drug reactions.