Neuroimaging abnormalities in Indian patients with uncontrolled partial seizures.

In this series we performed clinical and imaging evaluation of 77 consecutive patients with uncontrolled partial seizures. Single cerebral parenchymal calcification (22 patients) was the most common imaging abnormality. Nine patients had multiple punctate calcifications. Other CT abnormalities included persistence of granulomatous lesion (enhancing) or multiple cystic lesions. In nine patients (of 22 patients with a normal CT scan) magnetic resonance imaging (MRI) was done, and two patients were seen to have circumscribed cystic lesions in the temporal lobes. The causes for uncontrolled seizures in India are totally different and revolve around neurocysticercosis, as the parasite sometimes runs a very long course of evolution in the brain. Sequelae of neurocysticercosis in the form of calcification is often a focus of epileptogenicity.