Poliosis as the first clue of tuberous sclerosis.

Ash leaf hypopigment macules, until now, was known as earliest signs of tuberous sclerosis, unfortunately not always visible at birth. We reported herein a case of tuberous sclerosis presented with a tuft of white hair (poliosis) at birth for recommended poliosis as a useful earliest sign for detection of tuberous sclerosis in the newborn.