Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2011
Microstructural disruption of white matter in heroin addicts revealed by diffusion tensor imaging: a controlled study.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Wang Xuyi, Zhou Xuhui, Liao Yanhui, Tang Jinsong, Liu Tieqiao, Hao Wei
Аннотация
OBJECTIVE: To examine white matter integrity in heroin-dependent patients and matched normal controls with diffusion tensor imaging (DTI).
METHODS: The fractional anisotropy was compared between 15 heroin-dependent patients and 15 controls.
RESULTS: We found the fractional anisotropy was significantly decreased in specific brain regions of the heroin-dependent patients (P<0.001 uncorrected), including the frontal gyrus, the parietal lobule, the insula, and the corpus callosum.
CONCLUSION: The presence of microstructural abnormality is found in the white matter of several brain regions of heroin-dependent patients.
METHODS: The fractional anisotropy was compared between 15 heroin-dependent patients and 15 controls.
RESULTS: We found the fractional anisotropy was significantly decreased in specific brain regions of the heroin-dependent patients (P<0.001 uncorrected), including the frontal gyrus, the parietal lobule, the insula, and the corpus callosum.
CONCLUSION: The presence of microstructural abnormality is found in the white matter of several brain regions of heroin-dependent patients.