Does Adenovirus and Coxsackie B Virus Infection Play a Role in Tracheobronchopathia Osteochondroplastica (TO).

Background

Tracheobronchopathia osteochondroplastica (TO) is a rare benign disease. We report a case of TO.

Methods

Chest CT scan and bronchoscope with biopsy was performed for diagnosis and blood tests explored for the latent etiology.

Results

Chest CT scan and bronchoscopic images showed multiple nodular protrusions in the trachea and main bronchi. Histopathology demonstrated sub-mucosal ossification and inflammatory cell infiltration. Laboratory inspection showed adenovirus and coxsackie B virus IgM antibodies were positive.

Conclusions

The patient recently had a virus infection and inflammation was observed in histopathology, which indicated adenovirus and coxsackie B virus may play a role in the occurrence or exacerbation of TO.