MMWR. Morbidity and mortality weekly report · 2023
Acute Kidney Injury Among Children Likely Associated with Diethylene Glycol-Contaminated Medications - The Gambia, June-September 2022.
СтатьяНазвание и аннотация: Перевод в очереди
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Bastani Parsa, Jammeh Anna, Lamar Frederica, Malenfant Jason H, Adewuyi Peter, Cavanaugh Alyson M, Calloway Kimberly, Crisp Carolyn, Fofana Nuha, Hallett T Christy, Jallow Amadou, Muoneke Uzoamaka, Nyassi Momodou, Thomas Jerry, Troeschel Alyssa, Yard Ellen, Yeh Michael, Bittaye Mustapha
Аннотация
On July 26, 2022, a pediatric nephrologist alerted The Gambia's Ministry of Health (MoH) to a cluster of cases of acute kidney injury (AKI) among young children at the country's sole teaching hospital, and on August 23, 2022, MoH requested assistance from CDC. CDC epidemiologists arrived in The Gambia, a West African country, on September 16 to assist MoH in characterizing the illness, describing the epidemiology, and identifying potential causal factors and their sources. Investigators reviewed medical records and interviewed caregivers to characterize patients' symptoms and identify exposures. The preliminary investigation suggested that various contaminated syrup-based children's medications contributed to the AKI outbreak. During the investigation, MoH recalled implicated medications from a single international manufacturer. Continued efforts to strengthen pharmaceutical quality control and event-based public health surveillance are needed to help prevent future medication-related outbreaks.