Fibrinolysis in cyanotic and acyanotic children before and after open intracardiac operations with the Bently Temptrol oxygenator.

Fibrinolysis in cyanotic and acyanotic children has been studied before and after open intracardiac operations. Preoperatively, shorter lysis times were found in the cyanotic group. Lysis times in individual patients varied at different times before operation. Precise documentation of the timing of fibrinolysis determinations is necessary. The lysis times appear to be affected by variables such as fasting, stress, and anesthesia in addition to perfusion. Postoperatively there was no excessive fibrinolysis in either the cyanotic or acyanotic group, the groups showing no differences. No significant alterations in plasma fibrinogen were present before or after perfusion with the pediatric Bentley Temptrol system.