Crosslinking konjac-glucomannan with kappa-carrageenan nanogels: A step toward the design of sacrificial materials.

The challenge in designing sacrificial materials is to obtain materials that are both mechanically stable and easily dissolvable. This research aimed to meet this challenge by fabricating a new polymer-nanogel hydrogel based solely on hydrogen bonds between two polysaccharides. The study focused on hydrogels formed from soluble konjac-glucomannan and nanogels synthesized from kappa-carrageenan. This novel hydrogel exhibited self-healing and shear-thinning properties due to its weak physical interactions. The hydrogel dissolved simultaneously with its swelling. Changes in temperature or nanogel concentration, or the addition of potassium ions, altered the swelling and dissolution rates. Furthermore, adding KCl to the as-prepared hydrogel increased its compression and tensile moduli and its strength. The new formulation opens numerous possibilities as a potential sacrificial material for different applications since it is mechanically stable yet rapidly dissolves in physiological conditions without applying high temperatures or using chelating agents.