Deutsche medizinische Wochenschrift (1946) · 2010
[Sarcoidosis, chronic obstructive pulmonary disease and viral hepatitis--a challenge for diagnostic and therapy].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gompelmann D R, Kappes J, Heussel C-P, Herth F J F
Аннотация
HISTORY AND CLINICAL FINDINGS: A 39-year-old smoker noted dyspnoea on exertion and had a dry cough.
INVESTIGATIONS: Pulmonary function test revealed a mainly obstructive ventilatory impairment with only discrete restrictive component. Computed tomography showed bilateral hilar and mediastinal adenopathy with pulmonary parenchymal abnormalities. Transbronchial lung biopsy revealed epitheloid granuloma with giant cells but no central necrosis. Blood tests showed HBs-antigen, anti-HBc-IgG, anti-HBe-IgG/IgM and hepatitis B-DNA.
DIAGNOSIS: These findings indicated pulmonary sarcoidosis, chronic obstructive pulmonary disease and chronic hepatitis-B-infection.
TREATMENT AND COURSE: Considering all revealed pneumological test results and the hepatitis-B-infection, glucocorticosteroids were thought not to be indicated.
CONCLUSION: Even when treatment of sarcoidosis is indicated, all arguments for and against treatment, in particular the presence of co-morbidities and possible negative effects of immunosuppression, should be carefully considered in the individual case before any treatment is initiated.
INVESTIGATIONS: Pulmonary function test revealed a mainly obstructive ventilatory impairment with only discrete restrictive component. Computed tomography showed bilateral hilar and mediastinal adenopathy with pulmonary parenchymal abnormalities. Transbronchial lung biopsy revealed epitheloid granuloma with giant cells but no central necrosis. Blood tests showed HBs-antigen, anti-HBc-IgG, anti-HBe-IgG/IgM and hepatitis B-DNA.
DIAGNOSIS: These findings indicated pulmonary sarcoidosis, chronic obstructive pulmonary disease and chronic hepatitis-B-infection.
TREATMENT AND COURSE: Considering all revealed pneumological test results and the hepatitis-B-infection, glucocorticosteroids were thought not to be indicated.
CONCLUSION: Even when treatment of sarcoidosis is indicated, all arguments for and against treatment, in particular the presence of co-morbidities and possible negative effects of immunosuppression, should be carefully considered in the individual case before any treatment is initiated.
Предметные рубрики MeSH
Administration, InhalationAdrenergic beta-AgonistsAdultBiopsyBlood Gas AnalysisBronchoscopyCholinergic AntagonistsComorbidityCoughDiagnosis, DifferentialDrug Therapy, CombinationDyspneaGlucocorticoidsHepatitis B, ChronicHumansImage Processing, Computer-AssistedLiver Function TestsLungMalePulmonary Disease, Chronic ObstructiveRespiratory Function TestsSarcoidosis, PulmonaryTomography, Spiral Computed