Angiomyolipoma of the large intestine: report of a case.

A case of an angiomyolipoma of the large intestine occurring in a 55-year-old man without evidence of tuberous sclerosis is reported. Endoscopically, the lesion resembled a sessile adenomatous polyp. The tumor measured 1 cm. Histologic examination revealed a lesion composed predominantly of spindle and epithelioid cells with significant nuclear atypia. Mitoses were rare. The tumor was strongly positive for HMB-45, CD68, vimentin, desmin, and smooth muscle actin. Rare scattered cells reacted with CD34. No residual tumor was found in the resected colon.