Cortisol excretion in high and low cynically hostile men.

Cynical hostility as measured by the Cook and Medley Hostility (Ho) Scale has been found in some studies to be associated with increased risk of life-threatening illness. Previous laboratory studies of cardiovascular reactivity have been consistent with the general hypothesis that increased physiological responsiveness is one possible mechanism underlying the association between hostility and health. The present study extended this previous research by evaluating urinary cortisol excretion during routine daily activities in a sample of high and low cynically hostile young men. Although high and low Ho groups did not differ in their cortisol excretion upon awakening, the high Ho group displayed more than twice the increase in cortisol excretion during daytime hours as that occurring among low hostile men. This difference dissipated during the evening hours. Results are discussed in terms of possible physiological mechanisms linking hostility and health.