Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics · 2010
Antibiotic susceptibility and resistance of the odontogenic microbiological spectrum and its clinical impact on severe deep space head and neck infections.
СтатьяНазвание и аннотация: Перевод в очереди
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Poeschl Paul W, Spusta Ludwig, Russmueller Guenter, Seemann Rudolf, Hirschl Alexander, Poeschl Ellen, Klug Clemens, Ewers Rolf
Аннотация
OBJECTIVE: The purpose of this retrospective study was to identify the major pathogens responsible for deep space head and neck infections and their current resistance to routinely used antibiotics in a university hospital setting.
STUDY DESIGN: A total of 206 patients suffering from odontogenic deep space infections were treated at our department by means of surgical intervention and intravenous administration of antibiotics.
RESULTS: The predominant bacteria were viridans group streptococci (VGS), staphylococci, Prevotella, Peptostreptococcus, and Bacteroides. In the aerobic spectrum, resistance against clindamycin was found in 18%, against macrolides in 14%, and against penicillin G in 7%. The anaerobes were resistant to clindamycin in 11%, to metronidazole in 6%, and to penicillin G in 8%.
CONCLUSION: The high resistance rate for clindamycin and macrolides was especially striking and may necessitate an adaptation of our antibiotic regime in the future.
STUDY DESIGN: A total of 206 patients suffering from odontogenic deep space infections were treated at our department by means of surgical intervention and intravenous administration of antibiotics.
RESULTS: The predominant bacteria were viridans group streptococci (VGS), staphylococci, Prevotella, Peptostreptococcus, and Bacteroides. In the aerobic spectrum, resistance against clindamycin was found in 18%, against macrolides in 14%, and against penicillin G in 7%. The anaerobes were resistant to clindamycin in 11%, to metronidazole in 6%, and to penicillin G in 8%.
CONCLUSION: The high resistance rate for clindamycin and macrolides was especially striking and may necessitate an adaptation of our antibiotic regime in the future.
Предметные рубрики MeSH
AdolescentAdultAgedAged, 80 and overBacteria, AnaerobicBacterial InfectionsChildChild, PreschoolColony Count, MicrobialDrug Resistance, BacterialFemaleFocal Infection, DentalHospitals, UniversityHumansMaleMicrobial Sensitivity TestsMiddle AgedNeckRetrospective StudiesStaphylococcusViridans StreptococciYoung Adult