Fertility and sterility · 2007
Ring chromosome 12 and severe oligospermia: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Martin J Ryan, Wold Anne, Taylor Hugh S
Аннотация
OBJECTIVE: To describe an unusual presentation of ring chromosome 12, which manifested as severe azoospermia, resulting in male infertility.
DESIGN: Case report.
SETTING: In vitro fertilization center at a tertiary care hospital.
PATIENT(S): A 27-year-old man diagnosed with unexplained azoospermia and ring chromosome 12 abnormality during a workup for primary infertility.
INTERVENTION(S): In vitro fertilization with preimplantation genetic diagnosis.
MAIN OUTCOME MEASURE(S): To confirm the importance of obtaining karyotypes in individuals with severe oligospermia.
RESULT(S): Full-term pregnancy after IVF using donor sperm.
CONCLUSION(S): Severe oligospermia and male infertility should be included in the spectrum of findings found in ring chromosome 12.
DESIGN: Case report.
SETTING: In vitro fertilization center at a tertiary care hospital.
PATIENT(S): A 27-year-old man diagnosed with unexplained azoospermia and ring chromosome 12 abnormality during a workup for primary infertility.
INTERVENTION(S): In vitro fertilization with preimplantation genetic diagnosis.
MAIN OUTCOME MEASURE(S): To confirm the importance of obtaining karyotypes in individuals with severe oligospermia.
RESULT(S): Full-term pregnancy after IVF using donor sperm.
CONCLUSION(S): Severe oligospermia and male infertility should be included in the spectrum of findings found in ring chromosome 12.