Emerging infectious diseases · 2002
An outbreak of Rift Valley fever in Northeastern Kenya, 1997-98.
СтатьяНазвание и аннотация: Перевод в очереди
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Woods Christopher W, Karpati Adam M, Grein Thomas, McCarthy Noel, Gaturuku Peter, Muchiri Eric, Dunster Lee, Henderson Alden, Khan Ali S, Swanepoel Robert, Bonmarin Isabelle, Martin Louise, Mann Philip, Smoak Bonnie L, Ryan Michael, Ksiazek Thomas G, Arthur Ray R, Ndikuyeze Andre, Agata Naphtali N, Peters Clarence J, World Health Organization Hemorrhagic Fever Task Force
Аннотация
In December 1997, 170 hemorrhagic fever-associated deaths were reported in Garissa District, Kenya. Laboratory testing identified evidence of acute Rift Valley fever virus (RVFV). Of the 171 persons enrolled in a cross-sectional study, 31(18%) were anti-RVFV immunoglobulin (Ig) M positive. An age-adjusted IgM antibody prevalence of 14% was estimated for the district. We estimate approximately 27,500 infections occurred in Garissa District, making this the largest recorded outbreak of RVFV in East Africa. In multivariable analysis, contact with sheep body fluids and sheltering livestock in one s home were significantly associated with infection. Direct contact with animals, particularly contact with sheep body fluids, was the most important modifiable risk factor for RVFV infection. Public education during epizootics may reduce human illness and deaths associated with future outbreaks.