[The Impact of Industrial Vibration on Level of Antibodies to Regulatory Proteins of Nervous Tissue.].

The characteristic peculiarities in changing the levels of autoantibodies (AB) to the regulatory proteins of the nervous tissue have been revealed in the workers with a long-term working period and in the patients with Vibration-induced disease (VID). The levels of AB to MPM, Ser-R and β2GP were higher than the border of physiological level and the levels of AB to proteins GFAP and S-100 were lower than a physiological level in the workers with a long-term working period and in the patients with VID. Thereto, the higher levels of AB to GAMK-R were revealed in the patients with VID 2 times as often and 4 times as often compared with the workers with a long-term working period. The changes in the content of AB to the regulatory proteins of the nervous tissue may, most probably, testify the sano- and pathogenesis changes in the functions of the immune system. The changes in the content of AB in the workers with a long-term working period without signs of health disorders due to exposure to vibration have allowed to state the starting changes and the already manifested pathological processes of a definite localization in the nervous tissue stipulated with a long-term exposure to vibration in the patients with VID.