Medicine · 2025
Uterine intermural adenosarcoma arising from adenomyoma: A case report and review of literature.
СтатьяКлинический случайОбзорНазвание и аннотация: Перевод в очереди
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Qiu Jingwen, Yuan Li
Аннотация
RATIONALE: Intramural adenosarcoma of the uterine myometrium is an uncommon gynecologic malignancy, often diagnosed postoperatively, and may arise from pre-existing benign lesions such as adenomyoma.
PATIENT CONCERNS: A 46-year-old woman presented with irregular vaginal bleeding during the postmenstrual period for 3 months. She had a prior history of adenomyoma resection and breast cancer treated with tamoxifen.
DIAGNOSES: Pelvic ultrasonography suggested multiple uterine myomas. Histopathological and immunohistochemical analyses of the resected specimen confirmed low-grade malignant uterine adenosarcoma originating from adenomyoma.
INTERVENTIONS: The patient underwent a lower abdominal hysterectomy with bilateral adnexectomy.
OUTCOMES: Postoperative recovery was uneventful. No adjuvant therapy was administered, and the patient remains under regular oncology follow-up without recurrence to date.
LESSONS: This case highlights the potential for malignant transformation of adenomyoma into intramural adenosarcoma and underscores the importance of thorough histopathological evaluation in patients with recurrent or atypical uterine masses.
PATIENT CONCERNS: A 46-year-old woman presented with irregular vaginal bleeding during the postmenstrual period for 3 months. She had a prior history of adenomyoma resection and breast cancer treated with tamoxifen.
DIAGNOSES: Pelvic ultrasonography suggested multiple uterine myomas. Histopathological and immunohistochemical analyses of the resected specimen confirmed low-grade malignant uterine adenosarcoma originating from adenomyoma.
INTERVENTIONS: The patient underwent a lower abdominal hysterectomy with bilateral adnexectomy.
OUTCOMES: Postoperative recovery was uneventful. No adjuvant therapy was administered, and the patient remains under regular oncology follow-up without recurrence to date.
LESSONS: This case highlights the potential for malignant transformation of adenomyoma into intramural adenosarcoma and underscores the importance of thorough histopathological evaluation in patients with recurrent or atypical uterine masses.