Insulin pump therapy in the 21st century. Strategies for successful use in adults, adolescents, and children with diabetes.

Intensive diabetes management can be achieved in adults, adolescents, and children with use of CSII. Compared with MDI, CSII has better insulin pharmacokinetics, less variability in insulin absorption, and decreased risk of hypoglycemia; it also offers patients greater flexibility in lifestyle. Careful adjustment of basal and bolus doses and close follow-up, including patient education, are vital to the success of CSII.