Preliminary evaluation of the larvicidal activity of extracts and fractions from Ocotea nutans (Nees) Mez against Aedes aegypti.

INTRODUCTION

Aedes aegypti is the main vector of dengue and yellow fever. Recently, the use of plant-sourced larvicides has gained momentum.

METHODS

The hydroethanolic extracts and fractions ofOcotea nutansleaves and stems were bioassayed to determine the larvicidal efficacy of these samples.

RESULTS

S-HEX (hexane fraction from the crude stem extract) demonstrated high potential for controlling third-stage larvae, with an LC50 of 14.14 µg.mL-1 (concentration required to inhibit 50% of the treated larvae).

CONCLUSIONS

Extracts from O. nutans were effective against third-stage larvae ofA. aegyptiafter 24 h of exposure.