Extremely low-frequency magnetic fields (ELF-MF) and radiofrequency: Risk of childhood CNS tumors in a city with elevated ELF-MF exposure.

BACKGROUND

Central nervous system tumors (CNSTs) are the second most common childhood cancer. While their etiology is unclear, exposure to extremely low-frequency magnetic fields (ELF-MF) and radiofrequency (RF) may be associated with increased risk. This study aims to examine the relationship between ELF-MF and RF exposure and CNST risk in Mexico City's pediatric population.

METHODS

A case-control study was conducted in Mexico City (2017-2022), to assess ELF-MF and RF exposure in 200 CNST patients and 793 controls under 16 years old. Residential ELF-MF exposure was measured over 24 h, and RF exposure was assessed through the total duration of cell phone calls and electronic device usage (with and without internet). ELF-MF exposure levels below 0.1 μT and the lowest RF exposure quartile (Q1) served as reference groups for adjusted odds ratio (aOR) analyses. Data analysis was performed using R and SPSS software.

RESULTS

Of all participants, 5.1 % had ELF-MF exposure ≥0.3 μT. Elevated ELF-MF exposure (≥0.4 μT) was significantly associated with an increased risk of CNST (aOR (95 % confidence interval) = 2.39 (1.15-5.00). While cell phone use showed no differences between cases and controls, prolonged tablet use (with and without internet) was significantly associated with increased CNST risk (aOR = 2.53 (1.39-4.61), and 3.53 (1.45-8.59), respectively).

CONCLUSION

A high proportion of children in Mexico City are exposed to ELF-MF levels ≥0.3 μT, exceeding levels reported in other populations. Elevated residential ELF-MF exposure, as well as prolonged tablet use, both with and without internet connectivity, were significantly associated with an increased risk of developing CNST in childhood.