Tropical gastroenterology : official journal of the Digestive Diseases Foundation · 2010
Formalin instillation for uncontrolled radiation induced haemorrhagic proctitis.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Chattopadhyay Gautam, Ray Dipankar, Chakravartty Saurav, Mandal Subhayan
Аннотация
BACKGROUND: Radiation induced haemorrhagic proctitis is a well recognized complication of pelvic radiotherapy and its treatment is quite challenging.
AIM: To evaluate the efficacy of local instillation of 4% formalin in the management of uncontrolled radiation induced haemorrhagic proctitis.
METHODS: This prospective study included twenty-three patients who underwent formalin instillation. We documented the control of the symptoms, assessed the outcome of the treatment, presence of complications & long term results.
RESULTS: All patients were followed for a median of 13 months. In 15 patients, the bleeding stopped after a single treatment and in 6 after a second session. Only two patients required formalin instillation for the third time. During the follow-up period all patients were reviewed systemically with reference to the pretreatment complaints. No recurrent rectal bleeding occurred, bowel frequency was decreased and no further blood transfusion was required.
CONCLUSION: Local instillation of 4% formalin is an effective treatment for uncontrolled radiation induced haemorrhagic proctitis.
AIM: To evaluate the efficacy of local instillation of 4% formalin in the management of uncontrolled radiation induced haemorrhagic proctitis.
METHODS: This prospective study included twenty-three patients who underwent formalin instillation. We documented the control of the symptoms, assessed the outcome of the treatment, presence of complications & long term results.
RESULTS: All patients were followed for a median of 13 months. In 15 patients, the bleeding stopped after a single treatment and in 6 after a second session. Only two patients required formalin instillation for the third time. During the follow-up period all patients were reviewed systemically with reference to the pretreatment complaints. No recurrent rectal bleeding occurred, bowel frequency was decreased and no further blood transfusion was required.
CONCLUSION: Local instillation of 4% formalin is an effective treatment for uncontrolled radiation induced haemorrhagic proctitis.