MedElevator
Войти в исследования Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2026
Multicenter Retrospective Evaluation of the Use of Lyophilized Platelets in Dogs.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Nugen Sarah, Walton Rebecca A L, Smith Ryan, Cai Jiazhang, Mochel Jonathan P, Mays Erin Long
Аннотация
OBJECTIVE: The goal of this study was to describe the use of and complications associated with the administration of lyophilized platelets (LPs) in dogs with thrombocytopenia-associated hemorrhage and those with nonthrombocytopenia-associated hemorrhage. Secondary objectives were to report pretransfusion and posttransfusion values, including PCV, total plasma protein concentration, platelet count, blood product administration, and overall survival.
DESIGN: Retrospective study between 2018 and 2022.
SETTING: Two university veterinary teaching hospitals.
ANIMALS: Sixty-eight dogs that received LPs.
MEASUREMENTS AND MAIN RESULTS: Thirty-five dogs received LPs due to thrombocytopenia-associated hemorrhage, and 33 dogs received LPs due to nonthrombocytopenia-associated hemorrhage. The platelet count was lower in dogs with thrombocytopenia-associated hemorrhage, both before (p < 0.001) and after LP administration (p < 0.001), compared with dogs with nonthrombocytopenia-associated hemorrhage. Dogs with thrombocytopenia-associated hemorrhage had lower PCV values before LP administration (p = 0.007), but no difference was noted at 6-12 or 12-24 h after LP administration. There was no difference in the transfusion of other blood products (p = 0.620) or in survival to discharge (p = 1.000). Potential complications were noted in 6% of dogs.
CONCLUSIONS: LP administration may be considered for a variety of conditions, including both thrombocytopenia-associated hemorrhage and nonthrombocytopenia-associated hemorrhage.
DESIGN: Retrospective study between 2018 and 2022.
SETTING: Two university veterinary teaching hospitals.
ANIMALS: Sixty-eight dogs that received LPs.
MEASUREMENTS AND MAIN RESULTS: Thirty-five dogs received LPs due to thrombocytopenia-associated hemorrhage, and 33 dogs received LPs due to nonthrombocytopenia-associated hemorrhage. The platelet count was lower in dogs with thrombocytopenia-associated hemorrhage, both before (p < 0.001) and after LP administration (p < 0.001), compared with dogs with nonthrombocytopenia-associated hemorrhage. Dogs with thrombocytopenia-associated hemorrhage had lower PCV values before LP administration (p = 0.007), but no difference was noted at 6-12 or 12-24 h after LP administration. There was no difference in the transfusion of other blood products (p = 0.620) or in survival to discharge (p = 1.000). Potential complications were noted in 6% of dogs.
CONCLUSIONS: LP administration may be considered for a variety of conditions, including both thrombocytopenia-associated hemorrhage and nonthrombocytopenia-associated hemorrhage.