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Gan to kagaku ryoho. Cancer & chemotherapy · 2018

[Recurrent Gastric Cancer with Tumor Bleeding from a Metastatic Lymph Node Invading the Duodenal Stump Successfully Controlled by Palliative Radiotherapy-A Case Report].

Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Hamakawa Takuya, Nishikawa Kazuhiro, Hirao Motohiro, Tanaka Eiichi, Iwasaki Tetsuya, Shimoyama Ryo, Maeda Sakae, Fujiwara Ayako, Uemura Mamoru, Miyake Masakazu, Hama Naoki, Miyamoto Atsushi, Kato Takeshi, Takami Koji, Sekimoto Mitsugu

Аннотация

An 82-year-old man receiving oral administration of warfarin for atrial fibrillation underwent distal gastrectomy for advanced gastric cancer. The postoperative diagnosis was pT3(SS)N2M1H1P0CY0, pStage Ⅳ,(HER2, score 3+)gastric cancer. He received chemotherapy for the treatment of multiple liver metastases, following which, he developed lymph node metastases. Grade 3 anemia was observed at 46 months after initiation of chemotherapy when he was treated with third-line irinotecan plus cisplatin. Abdominal CT showed that CR for liver metastases and SD for lymph node metastases were maintained. Esophagogastroduodenoscopy and colonoscopy showed no intraluminal bleeding. As the anemia progressed, blood transfusion was required repeatedly instead of withdrawal of chemotherapy and replacement therapy of iron and vitamin B12. Double- balloon endoscopy revealed hemorrhagic tumor at duodenal stump. We diagnosed tumor bleeding from metastatic lymph node around pancreatic head invading to duodenum. Palliative radiotherapy(40 Gy/20 Fr)for hemostasis was performed. Finally, hemostasis and tumor shrinkage were achieved.

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