[Adverse events following immunization reported to the district sanitary-epidemiological station in Czestochowa in 2006-2010].

INTRODUCTION

Obligatory reporting of adverse effects following immunization (AEFI) was introduced in Poland in 1995. In 2006-2010 number of AEFI reported to the District Sanitary-Epidemiological Station in Czestochowa was 70. For the same period in the whole country 4552 cases were reported.

PURPOSE: Purpose of the study was to perform epidemiological analysis of cases reported in Czestochowa and to compare the results with the data for the whole country.

MATERIALS AND

METHODS

For analysis AEFI, data was obtained from the AEFI register held in PSSE in Czestochowa, and the data of National Institute of Public Health-PZH for 2006-2010. The analysis included the number and frequency of AEFI, the type of vaccine involved with the cases, and the character of the reaction.

RESULTS

Most frequently, AEFI reported to the PSSE occured after BCG vaccination--15 cases (21.4% of the total) and after DTP--14 cases (20%). AEFI other than BCG occurred in 55 cases, representing 78.6% of all reported. 37 AEFI (53% of all reported cases) was after vaccines with the pertussis component . In all instances, AEFI against measles, mumps and rubella occurred after the first dose of vaccine. In the analyzed period, it was observed steady increase in the total number of AEFI, which was associated with the increase in the number of infections covered by the vaccinations: Haemophilus influenzae type b, pneumococcal, varicella, human papillomavirus, and rotavirus. Adverse events following immunization reported in 2006-2010 to the PSSE in Czestochowa were mild reactions, which did not result in permanent adverse health complications. Trends for changes in the epidemiology ofAEFI in Czestochowa are similar to those in the the entire country.

CONCLUSION

The observed increase in the total number of AEFI is associated with an increase in the number of vaccinations performed in Poland.