Drug and alcohol dependence · 2026
A random intercept cross-lagged panel analysis of the relationships between substance use, depressive symptoms, and suicidal behavior.
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Ni Hanqing, Han Dongjun, Chen Xiaoyan, Zhu Ya, Shi Xuliang
Аннотация
OBJECTIVE: Although the association among substance use, depressive symptoms, and suicidal behavior has been investigated, the longitudinal bidirectional relation remains poorly understood, particularly with respect to distinguishing between-person and within-person effects, this study aimed to investigate the within-person longitudinal relationships between substance use, depressive symptoms, and suicidal behavior.
METHODS: This study used a longitudinal design to explore these associations among 5608 college students from two universities in a city in southern China (aged 17-22 years; Mage = 18.63 years, SD = 0.89; 48.2% females). Substance use was assessed using the Substance Use Questionnaire, depressive symptoms were measured with the 9-item Patient Health Questionnaire (PHQ-9), and suicidal behaviors were assessed using the Suicide Behavior Questionnaire-Revised (SBQ-R). The participants were assessed five times in a six-month interval over three years. Random intercept cross-lagged panel models (RI-CLPMs) were used to examine the within-person longitudinal relationships between substance use, depressive symptoms, and suicidal behavior.
RESULTS: The results of RI-CLPMs indicated that at the within-person level, suicidal behavior can positively predict subsequent depressive symptoms and substance use, significantly positively predicted subsequent depressive symptoms among females, but not substance use.
CONCLUSION: These results indicate that it is crucial to identify and address suicidal behavior among college students, as it can help prevent subsequent substance use and depressive symptoms.
METHODS: This study used a longitudinal design to explore these associations among 5608 college students from two universities in a city in southern China (aged 17-22 years; Mage = 18.63 years, SD = 0.89; 48.2% females). Substance use was assessed using the Substance Use Questionnaire, depressive symptoms were measured with the 9-item Patient Health Questionnaire (PHQ-9), and suicidal behaviors were assessed using the Suicide Behavior Questionnaire-Revised (SBQ-R). The participants were assessed five times in a six-month interval over three years. Random intercept cross-lagged panel models (RI-CLPMs) were used to examine the within-person longitudinal relationships between substance use, depressive symptoms, and suicidal behavior.
RESULTS: The results of RI-CLPMs indicated that at the within-person level, suicidal behavior can positively predict subsequent depressive symptoms and substance use, significantly positively predicted subsequent depressive symptoms among females, but not substance use.
CONCLUSION: These results indicate that it is crucial to identify and address suicidal behavior among college students, as it can help prevent subsequent substance use and depressive symptoms.