Global burden of disease related to tobacco products and trends projected: 1990-2021.

BACKGROUND

The use of tobacco products is considered to be one of the most serious public health threats worldwide, and this study aims to assess the global burden of various diseases caused by tobacco use, provide the necessary scientific basis for public health authorities, and propose tobacco control policies and interventions.

METHODS

This study analyzed the major burden of disease caused by tobacco products using the Global Burden of Disease (GBD) database from 1990 to 2021. Age Standardization Rate (ASR), annual Percentage Change (EAPC) were calculated using R4.2.3 software. Disease burden prediction analysis with the help of BAPC and INLA software packages.

RESULTS

The study findings indicated that from 1990 to 2021, the number of deaths and disability-adjusted life years (DALYs) attributable to tobacco products increased annually worldwide. Cardiovascular diseases and chronic respiratory diseases are the primary disease types caused by tobacco products, with the disease burden significantly higher in males than females. Significant disparities were observed between regions with different Socio-Demographic Index (SDI) levels. High SDI countries experienced more pronounced reductions in burden, whereas countries with low, middle, and middle-high SDI levels bore higher disease burdens. By 2040, the number of deaths and disease burden attributable to tobacco products globally is projected to continue increasing annually, albeit at a slower rate.

CONCLUSION

Despite a reduction in the global disease burden caused by tobacco, countries with low, middle, and middle-high SDI levels continue to bear a substantial burden.