Effect of a 5-year treatment program in patients with hyperoxaluric stones.

Hyperoxaluria, alone or associated with hypercalciuria, has been detected in 69 of 450 patients with recurrent stones (15.3 per cent). The 3 main findings associated with hyperoxaluria were 1) oxalate hyperabsorption, 2) hyperoxalemia and 3) increased or decreased oxalate clearance. Correction of oxalate hyperabsorption by administration of diethylaminoethanol cellulose showed good results through a 5-year followup. Succinimide, given to the hyperoxalemic group, and a combination of phosphate and magnesium, given to the group with altered clearances, showed poorer results.