[Mechanism of action of aldosterone on the toad bladder: correlation between biological response and occupation of the receptor sites].

The mechanism of aldosterone uptake in the epithelial cells of toad bladder was studied using mathematical modeling. It seems that two types of receptors are necessary to obtain a complete action of aldosterone. If this observation is confirmed, the traditional notion of type I receptors i.e. mineralocorticoids receptors and type II receptors i.e. glucocorticoids receptors has to be reviewed.