Primary malignant melanoma of the esophagus with multiple esophageal lesions.

BACKGROUND

A 48-year-old Chinese woman presented with a 2-month history of progressive dysphagia for solids, and (less frequently) liquids. She had minimal weight loss and no family history of cancer.

INVESTIGATIONS: Physical examination, conventional esophagogastroduodenoscopy, CT, fluorodeoxyglucose-PET, endoscopic ultrasonography, and histopathologic examination of excised tumor and biopsy specimens.

DIAGNOSIS: Primary malignant esophageal melanoma with submucosal infiltration but no distant metastasis.

MANAGEMENT: Endoscopic polypectomy followed by near-total esophagectomy with esophagogastric anastomosis.