Journal of the European Academy of Dermatology and Venereology : JEADV · 2014
Symptomatic dermographism: an inadequately described disease.
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Schoepke N, Młynek A, Weller K, Church M K, Maurer M
Аннотация
BACKGROUND: Symptomatic dermographism is the most common form of physical urticaria with a prevalence of 2-5%. However, its clinical picture has rarely been described.
OBJECTIVE: To understand more of patients' views about the practical aspects of their condition, its cause and impact on quality of life.
METHODS: Ninety-one of 150 patients with symptomatic dermographism from our specialist urticaria clinic completed a 38-question questionnaire sent them by mail.
RESULTS: The mean duration of disease was 6¼ years. In most patients, the condition was continuous, but ~25% had prolonged symptom-free phases. Severity was evaluated as moderate in 45%, severe in 33% and very severe in 6% of respondents. Other responses included: symptoms worse in the evening in 81%; quality of life significantly impaired in 44%; normal life not possible 7%; stress induces acute episodes 44%; other urticarial forms coexist 21%; allergy coexist 48%. A family history was reported in 14%. Almost all patients were taking H1 -anti-histamines, 49% getting marked improvement and 23% becoming symptoms free.
LIMITATIONS: It is a survey only of patient opinions.
CONCLUSIONS: This questionnaire survey confirmed that symptomatic dermographism is a debilitating condition with profound effects on quality of life but its underlying cause and disease mechanisms remain obscure.
OBJECTIVE: To understand more of patients' views about the practical aspects of their condition, its cause and impact on quality of life.
METHODS: Ninety-one of 150 patients with symptomatic dermographism from our specialist urticaria clinic completed a 38-question questionnaire sent them by mail.
RESULTS: The mean duration of disease was 6¼ years. In most patients, the condition was continuous, but ~25% had prolonged symptom-free phases. Severity was evaluated as moderate in 45%, severe in 33% and very severe in 6% of respondents. Other responses included: symptoms worse in the evening in 81%; quality of life significantly impaired in 44%; normal life not possible 7%; stress induces acute episodes 44%; other urticarial forms coexist 21%; allergy coexist 48%. A family history was reported in 14%. Almost all patients were taking H1 -anti-histamines, 49% getting marked improvement and 23% becoming symptoms free.
LIMITATIONS: It is a survey only of patient opinions.
CONCLUSIONS: This questionnaire survey confirmed that symptomatic dermographism is a debilitating condition with profound effects on quality of life but its underlying cause and disease mechanisms remain obscure.
Предметные рубрики MeSH
Activities of Daily LivingAdolescentAdultAgedComorbidityFatigueFemaleHeadacheHistamine H1 AntagonistsHumansHypersensitivity, ImmediateMaleMiddle AgedPruritusQuality of LifeRheumatic DiseasesSeverity of Illness IndexStress, PsychologicalSurveys and QuestionnairesThyroid DiseasesTime FactorsUrticariaYoung Adult