Vitiligo-epidemiological study of 4134 patients at the National Center for Vitiligo and Psoriasis in Central Saudi Arabia.

OBJECTIVE

To assess the clinical patterns, epidemiological profile of vitiligo, and its awareness among Saudi nationals.

METHODS

A retrospective study was conducted among Saudi nationals with a confirmed diagnosis of vitiligo presenting to the National Center for Vitiligo and Psoriasis, Riyadh, Saudi Arabia, from August 2002 to August 2006 using a retrospective questionnaire based on the history and medical records of patients.

RESULTS

Of the 4134 cases, 53.5% were females. The mean age of onset of vitiligo was 17.4 years. Vitiligo vulgaris was the most common type in 42.3% of cases, 90.5% had no associated autoimmune conditions. The family history was positive in 42.8%. Twenty-nine percent developed depigmentation on multiple sites, and 68.2% over exposed areas. Nearly 1912 (46.2%) were not aware of its cause, and 2682 (64.9%) were unaware of aggravating factors. Stress as an aggravating factor was considered by 15.1%. Herbal treatments were considered very effective by 45.8%.

CONCLUSION

Vitiligo is affecting Saudi women more than men with an early age of onset. Vitiligo vulgaris being the most prevalent form with a high rate of positive family history and low rate of associated autoimmune diseases. Knowledge of genetic and environmental factors affecting vitiligo is poorly conveyed and explored.