Familial cholesteatoma in East Anglia, UK.

OBJECTIVE

To report a cluster of families affected by cholesteatoma in the East Anglia region of the UK.

SETTING

Otology service for the population of Norfolk and North Suffolk, East Anglia, UK.

METHOD: Prospective and systematic collection of family history data for patients presenting with cholesteatoma over 10 years.

RESULT: Several families were identified with affected individuals over several generations.

CONCLUSION

There is likely to be a genetic propensity for cholesteatoma in some individuals.