Extraction and characterization of mango peel pectin as pharmaceutical excipient.

AIM OF STUDY: Present study includes extraction and characterization the mango peel derived pectin as a pharmaceutical excipients.

MATERIAL AND

METHODS

Pectin was obtained using acidified water based extraction in soxhlet apparatus. To characterize the extracted pectin phytochemical screening was done and micromeritic properties, flow behavior, surface tension, viscosity and swelling index were calculated.

RESULTS

Using water based extraction method 25.26% yield of pectin was obtained. The result revealed the fact that extracted mango peel pectin exhibited good flow properties (angle of repose 28.01), 41.90 +/- 2.62 dynes/cm2 surface tension, 0.46% w/w total ash, 0.76% loss on drying and pH was found 4.15, showed that this can be used in dosage form, without any irritation. Extracted pectin was soluble in warm water while insoluble in organic solvents.

CONCLUSIONS

Results of evaluated parameters showed that mango peel derived pectin can be used as pharmaceutical excipient to prepare solid oral dosage form.