Ocular immunology and inflammation · 2019
Development of Vitreoretinal Lymphoma in a Patient with Sarcoid Uveitis.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Wartique Lucie, Jamilloux Yvan, De Parisot De Bernecourt Audrey, Kodjikian Laurent, Ghesquieres Hervé, Ide Christophe, Sève Pascal
Аннотация
PURPOSE: The purpose of this article is to report the first case of primary vitreoretinal lymphoma in a patient with sarcoid uveitis.
MATERIAL AND METHODS: A 63-year-old woman with biopsy-proven sarcoid uveitis diagnosed 7 years ago was presented for a 6-month history of bilateral intermediate uveitis and gait disturbance with cerebral magnetic resonance imaging suggestive of neurosarcoidosis. Because of corticoids resistance, a vitrectomy and a cerebral biopsy were performed. The final diagnosis was primary central nervous system diffuse lymphoma. Patient died despite the chemotherapy with an initial improvement of visual and neurological features.
CONCLUSION: Ophthalmologists should know that patient followed up with sarcoid uveitis can develop a primary vitreoretinal diffuse large B-cell lymphoma.
MATERIAL AND METHODS: A 63-year-old woman with biopsy-proven sarcoid uveitis diagnosed 7 years ago was presented for a 6-month history of bilateral intermediate uveitis and gait disturbance with cerebral magnetic resonance imaging suggestive of neurosarcoidosis. Because of corticoids resistance, a vitrectomy and a cerebral biopsy were performed. The final diagnosis was primary central nervous system diffuse lymphoma. Patient died despite the chemotherapy with an initial improvement of visual and neurological features.
CONCLUSION: Ophthalmologists should know that patient followed up with sarcoid uveitis can develop a primary vitreoretinal diffuse large B-cell lymphoma.