Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2005
Otologic disease in turner syndrome.
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Dhooge Ingeborg J M, De Vel E, Verhoye C, Lemmerling M, Vinck B
Аннотация
OBJECTIVE: This study involved the assessment of the otologic and audiologic characteristics of a group of patients with Turner syndrome.
STUDY DESIGN: Prospective study consisting of a questionnaire (77 of 123 responders) and an otologic and audiologic evaluation in patients with Turner syndrome (41 participants).
SETTING: Tertiary academic medical setting.
PATIENTS: Children, adolescents, and adults with Turner syndrome (median age, 24 yr).
INTERVENTIONS: Otomicroscopy, audiometry, immittance measurements, and diagnostic imaging.
RESULTS: Otologic disease is an important characteristic in Turner syndrome. Sixty-six percent of the patients studied via the questionnaire reported a history of chronic or recurrent middle ear disease. Analysis of audiometric data in 40 patients tested reveals an equal amount of normal ears (38.8%) and pure sensorineural ears (38.8%), each constituting approximately one-third of the patient population. Pure conductive losses represent only one-fifth (21.3%) of auditory abnormality encountered.
CONCLUSIONS: Careful follow-up during early childhood of children with Turner syndrome is necessary to detect middle ear disease and prevent sequelae. However, long-term periodic review is mandatory even after resolution of middle ear disease to detect sensorineural hearing loss.
STUDY DESIGN: Prospective study consisting of a questionnaire (77 of 123 responders) and an otologic and audiologic evaluation in patients with Turner syndrome (41 participants).
SETTING: Tertiary academic medical setting.
PATIENTS: Children, adolescents, and adults with Turner syndrome (median age, 24 yr).
INTERVENTIONS: Otomicroscopy, audiometry, immittance measurements, and diagnostic imaging.
RESULTS: Otologic disease is an important characteristic in Turner syndrome. Sixty-six percent of the patients studied via the questionnaire reported a history of chronic or recurrent middle ear disease. Analysis of audiometric data in 40 patients tested reveals an equal amount of normal ears (38.8%) and pure sensorineural ears (38.8%), each constituting approximately one-third of the patient population. Pure conductive losses represent only one-fifth (21.3%) of auditory abnormality encountered.
CONCLUSIONS: Careful follow-up during early childhood of children with Turner syndrome is necessary to detect middle ear disease and prevent sequelae. However, long-term periodic review is mandatory even after resolution of middle ear disease to detect sensorineural hearing loss.
Предметные рубрики MeSH
AdolescentAdultAudiometry, Pure-ToneAuditory ThresholdBone ConductionChildChild, PreschoolEar DiseasesEar, ExternalEar, MiddleFemaleFollow-Up StudiesHearing Loss, ConductiveHearing Loss, SensorineuralHumansKaryotypingMaleMiddle AgedMosaicismOtitis MediaOtoacoustic Emissions, SpontaneousProspective StudiesSpeech Discrimination TestsTurner Syndrome