Early and mid-term outcomes of carotid angioplasty and stent placement in 579 patients.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Borhani-Haghighi Afshin, Hooshmandi Etrat, Zahediasl Farzaneh, Molavi Vardanjani Hossein, Rezaei Mahdiyeh, Rahimi-Jaberi Abbas, Ashjazadeh Nahid, Petramfar Peyman, Ostovan Vahid Reza, Fadakar Nima, Poursadeghfard Maryam, Izadi Sadegh, Nazeri Masoumeh, Zafarmand Seyedeh Shaghayegh, Bayat Mahnaz, Salehi Mohammad Saied, Owjfard Maryam, Sedighi Behnaz, Iranmanesh Farhad, Shafiei Kaveh, Vakilian Alireza, Moghadam Ahmadi Amir, Nemati Reza, Rezaeian Jahromi Fatemeh, Jalalijahromi Maryam, Kashani Kaveh, Razmeh Saeed, Bahrehbar Mansour, Basir Marzieh, Qureshi Adnan I
Аннотация
METHODS: This is a retrospective cohort study conducted at Shiraz University of Medical Sciences from March 2011 to March 2019. Patients at high risk and standard risk for carotid endarterectomy were included. The primary composite outcome was defined as stroke, myocardial infarction (MI), and death in the first 30 days after CAS. All-cause mortality, vascular mortality, and stroke were investigated during mid-term follow-up.
RESULTS: A total of 579 patients (618 CAS) were recruited (mean age: 71.52 years). Overall, 394 (68.40%), 211 (36.63%), 179 (31.07%), and 96 (16.72%) patients had hypertension, dyslipidemia, diabetes mellitus, or were cigarette smokers, respectively. Primary composite outcomes were observed in 2.59% of patients (1.55% stroke, 0.69% MI, and 1.72% death). Atrial fibrillation was a predictor of primary composite outcome in multivariate logistic regression (p = .048). The presence of total occlusion in the contralateral carotid artery was significantly associated with the risk of stroke in univariate logistic regression (p = .041). The patients were followed for a period ranging from 1 to 83 months. The overall survival rate for all-cause mortality was 93.48% at 1 year, 77.24% at 5 years, and 52.92% at 8 years. All-cause mortality was significantly higher among patients with symptomatic carotid stenosis (p = .014).
CONCLUSION: CAS provides acceptable short-term and mid-term outcomes in a unique population of high- and standard-surgical-risk, symptomatic and asymptomatic, octogenarian, and nonoctogenarian patients.