Revista medica de Chile · 2011
[Association between a cardiovascular risk score and early markers of atherosclerotic disease in Chilean children].
СтатьяВалидационное исследованиеНазвание и аннотация: Перевод в очереди
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Arnaiz Pilar, Pino Felipe, Marín Arnaldo, Barja Salesa, Aglony Marlene, Cassis Berta, Navarrete Carlos, Acevedo Mónica
Аннотация
BACKGROUND: A cardiovascular risk score for children, that includes traditional risk factors, obesity, sedentary habits and a family history of cardiovascular disease, has been recently proposed by Spanish researchers.
AIM: To apply this score in school age children in Santiago de Chile and correlate its results with markers of subclinical atherosclerotic disease.
MATERIAL AND METHODS: Retrospective analysis of data obtained from 209 children, aged 11.5 ± 2 years, studied between 2005 and 2006. Weight, height, blood pressure, ultrasound measurement of carotid intimamedia thickness and fow mediated dilatation of brachial artery and ultrasensible C reactive protein (us PCR) were measured. The Spanish cardiovascular risk score was calculated and correlated with ultrasound parameters and C reactive protein.
RESULTS: According to the score, 173 children (83%) had a low cardiovascular risk, 28 (13%) an intermediate risk and 8 (4%) a high risk. There was no association between the cardiovascular risk score and carotid intima-media thickness, fow mediated arterial dilatation and us PCR.
CONCLUSIONS: No significant association was observed between the proposed cardiovascular risk score and early markers of atherosclerotic disease in this group of children.
AIM: To apply this score in school age children in Santiago de Chile and correlate its results with markers of subclinical atherosclerotic disease.
MATERIAL AND METHODS: Retrospective analysis of data obtained from 209 children, aged 11.5 ± 2 years, studied between 2005 and 2006. Weight, height, blood pressure, ultrasound measurement of carotid intimamedia thickness and fow mediated dilatation of brachial artery and ultrasensible C reactive protein (us PCR) were measured. The Spanish cardiovascular risk score was calculated and correlated with ultrasound parameters and C reactive protein.
RESULTS: According to the score, 173 children (83%) had a low cardiovascular risk, 28 (13%) an intermediate risk and 8 (4%) a high risk. There was no association between the cardiovascular risk score and carotid intima-media thickness, fow mediated arterial dilatation and us PCR.
CONCLUSIONS: No significant association was observed between the proposed cardiovascular risk score and early markers of atherosclerotic disease in this group of children.