[The effects of low birth weight, gestational age on lung function in childhood].

OBJECTIVE

To evaluate the effects of low birth weight, gestational age on lung function in later childhood.

METHODS

Height, body weight and lung function were measured in a cohort of 35 children with low birth weight (aged 6 approximately 9 y) and 35 healthy controls matched for sex and age with normal birth weight. At the same time, we inquired their gestational age and passive smoking history. The correlation analysis was used to analyze the relationship between lung function in these children and birth weight and gestational age.

RESULTS

FVC, FEV(1), FEV(1)% pred, V(75), V(50), V(50%) Pred, (V(25%) Pred in children with low birth weight were significantly lower than those in children with normal birth weight (P < 0.05). The lung function statistically positively correlated with birth weight (r = 0.245 approximately 0.365, P < 0.05), but not with gestational age (P > 0.05).

CONCLUSION

Low birth weight was positively correlated with most lung function parameters in childhood.