[Manuel Julián Grajales: propagator of smallpox vaccine in South America. Anatomist and surgeon].

Grajales came to Chile in December 1807, noting that since 1805 smallpox vaccination had been introduced by Fray Pedro Manuel Chaparro, supported by the Councilor Nicholas Matorras. He founded the Vaccination Boards of Valparaiso and Santiago in 1808 and became professor of anatomy and surgery in 1819. In 1823 he received his authorization to practice medicine. He wanted to finish his medical studies at the University of San Marcos in Lima, but the war of Independence made this impossible. He returned to Spain in 1825. In 1848, he became Member of Honor of the Faculty of Medicine, Universidad de Chile.