Allergologia et immunopathologia · 2003
The association between delayed type hypersensitivity reaction to Mycobacterium tuberculosis and atopy in asthmatic children.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Nuhoglu Y, Nuhoglu C, Ozcay S
Аннотация
BACKGROUND: It has been postulated that there is an inverse association between mycobacterium tuberculosis infection and atopy. We aimed to investigate if there is a similar relation in our study group, consisting 252 asthmatic children.
METHODS: In tuberculin testing indurations greater than or equal to 5 mm were accepted as positive. The most common aeroallergens were used in skin prick testing and reactions > or = 3 mm were accepted as positive.
RESULTS: In 139 patients PPD was negative, where as in 113 patients PPD was positive. Among the PPD (-) patients skin prick test was positive in 64 % (n = 89). Among the PPD (+) patients skin prick test was positive in 71 % (n = 80). As the two groups were compared for having positive skin prick test reactions no statistically significant difference was detected between them (p = 0.283).
CONCLUSIONS: Tuberculin reactivity is not inversely associated with atopy in asthmatic children.
METHODS: In tuberculin testing indurations greater than or equal to 5 mm were accepted as positive. The most common aeroallergens were used in skin prick testing and reactions > or = 3 mm were accepted as positive.
RESULTS: In 139 patients PPD was negative, where as in 113 patients PPD was positive. Among the PPD (-) patients skin prick test was positive in 64 % (n = 89). Among the PPD (+) patients skin prick test was positive in 71 % (n = 80). As the two groups were compared for having positive skin prick test reactions no statistically significant difference was detected between them (p = 0.283).
CONCLUSIONS: Tuberculin reactivity is not inversely associated with atopy in asthmatic children.