Lack of association of atopic dermatitis severity and morphology with asthma onset and control.

BACKGROUND

Asthma is one of the most well-recognized comorbidities of atopic dermatitis (AD). However, the relationship of AD severity and morphology with asthma characteristics in adults is not well defined.

OBJECTIVES

To understand associations of AD severity and morphology with comorbid asthma age-of-onset and control in adults with AD.

METHODS

A cross-sectional, dermatology practice-based study was performed in adults (≥ 18 years) with AD and history of asthma (N = 252). Self-administered electronic questionnaires were completed by patients, including demographics, patient-reported outcomes measures of AD severity, history of asthma, age-of-onset, and Asthma Control Test (ACT). Multivariable logistic regression models were constructed to examine relationships between AD severity and morphology with asthma age-of-onset and control.

RESULTS

The mean ± standard deviation ACT score was 21.7 ± 4.3 (range 5-25), with 55 (21.8%) having ACT scores ≤ 19 indicating poorly controlled asthma. AD severity and morphology were not associated with adult-onset asthma or poor asthma control.

CONCLUSIONS

AD severity and morphology were not consistently associated with comorbid asthma age-of-onset or control in adults with AD.