Wiadomosci lekarskie (Warsaw, Poland : 1960) · 2026
Designing and molecular docking analysis of newly acetazolamide derived compounds integrating 4-oxothiazolidine group as possible carbonic anhydrase deactivators.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ayoub Shaymaa Abdul Zahra, Aldabagh Noor H Naser, Atiya Rana Neama
Аннотация
OBJECTIVE: Aim: To investigate immunological markers that may be associated with measles viral infections in aborted women, specifically cytokines IL-10 and IL-17.
PATIENTS AND METHODS: Materials and Methods: From October 2024 to the end of December 2024, the study included 352 participants, comprising 176 females with a history of abortions and 176 females with normal pregnancies, who acted as a control group. Serum samples were analyzed for IL-10 and IL-17 using the enzyme-linked immunosorbent assay (ELISA) method.
RESULTS: Results: The serum level of IL-10 was significantly lower in women with abortion compared to the control group, with a median of 216.02 pg/ml versus 329.79 pg/ml, respectively (p<0.001). Similarly, the serum level of IL-17 was significantly higher in women with abortion compared to the control group, with a median of 85.24 pg/ml versus 51.76 pg/ml, respectively p<0.001).
CONCLUSION: Conclusions:The main clinical features of a viral infection, such as measles, during pregnancy are fever. Correlation of IL-10 and IL-17 to measles infection in the control group: Measles IgM and IgG showed no significant correlation to IL-10 and IL-17 (p>0.05). In the abortion group, measles IgM and IgG showed significant positive correlation to IL-10 and IL-17 p<0.001, finally, family history is a significant risk factor for abortion.
PATIENTS AND METHODS: Materials and Methods: From October 2024 to the end of December 2024, the study included 352 participants, comprising 176 females with a history of abortions and 176 females with normal pregnancies, who acted as a control group. Serum samples were analyzed for IL-10 and IL-17 using the enzyme-linked immunosorbent assay (ELISA) method.
RESULTS: Results: The serum level of IL-10 was significantly lower in women with abortion compared to the control group, with a median of 216.02 pg/ml versus 329.79 pg/ml, respectively (p<0.001). Similarly, the serum level of IL-17 was significantly higher in women with abortion compared to the control group, with a median of 85.24 pg/ml versus 51.76 pg/ml, respectively p<0.001).
CONCLUSION: Conclusions:The main clinical features of a viral infection, such as measles, during pregnancy are fever. Correlation of IL-10 and IL-17 to measles infection in the control group: Measles IgM and IgG showed no significant correlation to IL-10 and IL-17 (p>0.05). In the abortion group, measles IgM and IgG showed significant positive correlation to IL-10 and IL-17 p<0.001, finally, family history is a significant risk factor for abortion.