Stereotactic Radiosurgery Versus Observation in Small- and Medium-Sized Vestibular Schwannoma Patients With Normal Hearing: A Retrospective International Multicenter Study.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Hajikarimloo Bardia, Bin-Alamer Othman, Tos Salem M, Mantziaris Georgios, Ishaque Mariam, Abou-Al-Shaar Hussam, Peker Selcuk, Samanci Yavuz, Pelcher Isabelle, Begley Sabrina, Goenka Anuj, Schulder Michael, Tourigny Jean-Nicolas, Mathieu David, Hamel Andréanne, Briggs Robert G, Yu Cheng, Zada Gabriel, Giannotta Steven L, Speckter Herwin, Palque Sarai, Tripathi Manjul, Kumar Saurabh, Kaur Rupinder, Kumar Narendra, Rogowski Brandon, Shepard Matthew J, Johnson Bryan A, Trifiletti Daniel M, Warnick Ronald E, Mashiach Elad, De Nigris Vasconcellos Fernando, Bernstein Kenneth, Schnurman Zane, Alzate Juan, Kondziolka Douglas, Sheehan Jason P
Аннотация
METHODS: In this multicenter international study, we retrospectively analyzed the hearing, radiological, and neurological outcomes of patients who underwent SRS (SRS group) or OBS (OBS group). The cohorts were matched using propensity scores based on age, sex, tumor volume, pure-tone average, and speech discrimination score at a 1:1 ratio without replacement.
RESULTS: After matching, each group comprised 57 patients. The median follow-up was 49 and 37 months for the SRS and the OBS groups, respectively ( P = .3). The 5- and 9-year serviceable hearing preservation rates in the SRS group were 76.2% and 42.4% vs 56.1% and 16.8% in the OBS group ( P = .17). Class A preservation occurred in 57.9% (33/57) of the SRS and 52.6% (30/57) of the OBS cohorts ( P = .70). Regarding the TC rates, SRS was associated with significantly higher TC rates ( P < .0001).
CONCLUSION: We found that SRS is significantly superior regarding TC and provided noninferior hearing outcomes compared with OBS in VS patients with American Academy of Otolaryngology-Head and Neck Surgery class A hearing at presentation. Therefore, we suggest performing SRS in individuals with VS and normal hearing function.