Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2007
The use of typhoid vaccines in Asia: the DOMI experience.
СтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ochiai R Leon, Acosta Camilo J, Agtini Magdarina, Bhattacharya Sujit K, Bhutta Zulfiqar A, Do Canh Gia, Dong Baiqing, Chen Xinguang, Stanton Bonita, Kaljee Linda, Nyamete Andrew, Galindo Claudia M, von Seidlein Lorenz, DeRoeck Denise, Jodar Luis, Clemens John D
Аннотация
BACKGROUND: Two currently licensed typhoid vaccines have been evaluated in Asia, yet few Asian countries have considered including typhoid vaccines in their vaccination programs. The Diseases of the Most Impoverished (DOMI) Program was initiated to provide evidence to decide on the introduction of typhoid vaccines in Asian countries.
METHODS: The centerpiece of the program is a multidisciplinary demonstration project with Vi vaccine in 5 Asian countries. The project includes epidemiologic, economic, sociobehavioral, and policy studies.
RESULTS: Policy makers want evidence on which to base their vaccine-related decisions. The DOMI Program has provided updated information on the typhoid fever burden at several Asian sites. Cost-of-illness studies found high costs to governments and individuals. Sociobehavioral studies indicated a positive attitude toward typhoid vaccines. The results of the demonstration projects indicate that mass-immunization campaigns are feasible and acceptable.
CONCLUSIONS: The DOMI Program has begun to provide momentum for the evidence-based, rational introduction of typhoid vaccines into the public health programs of several Asian countries.
METHODS: The centerpiece of the program is a multidisciplinary demonstration project with Vi vaccine in 5 Asian countries. The project includes epidemiologic, economic, sociobehavioral, and policy studies.
RESULTS: Policy makers want evidence on which to base their vaccine-related decisions. The DOMI Program has provided updated information on the typhoid fever burden at several Asian sites. Cost-of-illness studies found high costs to governments and individuals. Sociobehavioral studies indicated a positive attitude toward typhoid vaccines. The results of the demonstration projects indicate that mass-immunization campaigns are feasible and acceptable.
CONCLUSIONS: The DOMI Program has begun to provide momentum for the evidence-based, rational introduction of typhoid vaccines into the public health programs of several Asian countries.
Предметные рубрики MeSH
Administration, OralAdolescentAdultAsiaChildChild, PreschoolCost of IllnessDeveloping CountriesDrug Administration ScheduleEpidemiologic StudiesEvidence-Based MedicineHealth PolicyHumansImmunization ProgramsMass VaccinationMiddle AgedPolysaccharides, BacterialPoverty AreasProspective StudiesTyphoid FeverTyphoid-Paratyphoid VaccinesVaccines, AttenuatedZea mays